１．ABBONDANDOLO, A.  (1977) Prospects for evaluating genetic damage in mammalian cells in culture.  Mutat. Res., 42: 279-298.ABRAHAMSON, S. & LEWIS, E.B.  (1971) The detection of mutations in  Drosophila melanogaster.  In: Hollaender, A., ed. Chemical mutagens: principles and methods for their detection, New York, London, Plenum Press, pp. 461-487.

２．ADAIR, G.M., CARVER, J.H., & WANDRES, D.L.  (1980)  Mutagenicity testing in mammalian cells. I. Derivation of a Chinesehamster ovary cell line heterozygous for the adenine phosphoribosyl transferase and thymidine kinase loci.  Mutat. Res.,72: 187-205.

３．ADLER, I.-D.  (1970)  Cytogenic analysis of Ascites tumour cells in mice in mutation research. In: Vogel, F. & Rohrborn, G., ed.  Chemical mutagenesis in mammals and man, Berlin, Heidelberg, New York, Springer-Verlag, pp. 251-259.

４．ADLER, I.-D.  (1974)  Comparative cytogenetic study after treatment of mouse spermatogonia with mitomycin C.  Mutat. Res.,23: 369-379.

５．ADLER, I.-D.  (1981)  Transplacental cytogenetic effects by TEM, mitomycin C, and benzo(a)pyrene. Mutat. Res.,85: 299-300.

６．ADLER, I.-D.  (1982)  Male germ cell cytogenetics. In: Hsu, T.C., ed.  Cytogenetic assays of environmental mutagens, New York, Allanheld Osmun & Co., pp. 249-276.

７．ADLER, I.-D.  (1985)  Cytogenetic tests in mammals. In: Venitt, S. & Parry, J.M., ed.  Mutagenicity testing: a  practical approach, Oxford, IRL Press, pp. 275-306.

８．ADLER, I.-D. & BREWEN, J.G.  (1982)  Effects of chemicals on chromosome aberration production in male and female germcells. In: Hollaender, A. & de Serres, F.J., ed.  Chemical mutagens: principles and methods for their detection, New York,London, Plenum Press, Vol. 7, pp. 1-35.

９．AHMED, M. & GRANT, W.F.  (1972)  Cytological effect of the pesticides Phosdrin and Bladex on  Tradescantia and  Vicia  faba. Can. J. Genet. Cytol., 14: 157-165.

１０．ALBANESE, R., TOPHAM, J.C., EVANS, E., CLARE, M.G., & TEASE, C.  (1984)  Mammalian germ cell cytogenetics. In: Dean, B.J., ed.  UKEMS Sub-Committee on Guidelines for Mutagenicity  Testing. Part II. Supplementary Tests, Swansea, United Kingdom Environmental Mutagen Society.

１１．AMACHER, D.E. &PAILLET, S.C.  (1983)  The activation of procarcinogens to mutagens by cultured rat hepatocytes in the L5178Y/TK mutation assay.  Mutat. Res., 113: 77-88.

１２．AMACHER, D.E. & TURNER, G.N.  (1981)  Promutagen activation by rodent-liver post-mitochondrial fractions in the L5178Y/TK cell mutation assay.  Mutat. Res., 74: 485-501.

１３．AMACHER, D.E. & TURNER, G.N.  (1982a)  Mutagenic evaluation of carcinogens and non-carcinogens in the L5178Y/TK assay utilizing post-mitochondrial fractions (S9) from normal rat liver.  Mutat. Res., 97: 49-65.

１４．AMACHER, D.E. & TURNER, G.N.  (1982b)  The effect of liver post-mitochondrial fraction concentration from Arochlor 1254-treated rats on promutagen activation in L5178Y cells. Mutat. Res., 97: 131-137.

１５．AMES, B.N., DURSTEN, W.E., YAMASAKI, E., & LEE, F.W.  (1973)  Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.  Proc. Natl Acad. Sci. (USA), 70: 2281-2285.

１６．AMES, B.N., MCCANN, J., & YAMASAKI, E.  (1975)  Methods for detecting carcinogens and mutagens with the  Salmonella/mammalian microsome mutagenicity test.  Mutat. Res., 31: 347-364.

１７．ANDERSON, D., BATEMAN, A., & MCGREGOR, D.  (1983)  Dominant lethal mutation assays. In:  Report of the UKEMS Sub-Committee on Guidelines for Mutagenicity Testing, Swansea, United Kingdom Environmental Mutagen Society, pp. 143-164.

１９．NDRAE, U. & GREIM, H.  (1979)  Induction of DNA repair replication by hydroxyurea in human lymphoblastoid cellsmediated by liver micromes and NADPH.  Biochem. biophys. Res. Commun., 87: 50-58.

２０．ASHBY, J., DE SERRES, F.J., DRAPER, M., ISHIDATE, M. Jr, MARGOLIN, B.H, MATTER, B.E., & SHELBY, M.D., ed.  (1985)  Evaluation of short-term tests for carcinogens. Report of the International Programme on Chemical Safety's Collaborative Study on In vitro Assays, Amsterdam, Oxford, New York, Elsevier Science Publishers (Progress in Mutation Research, Vol. 5)

２１．AUERBACH, C  (1962a)   Mutation. An introduction to research on mutagenesis. Part 1. Methods, Edinburgh, London, Oliver and Boyd, 176 pp.

２２．AUERBACH, C.  (1962b)  The production of visible mutations in  Drosophila by chloroethyl methylsulfonate (CB 1506).  Genet. Res., 3: 461-466.

２３．BAKER, R.M.  (1979)  Nature and use of ouabain-resistant mutants. In: Hsie, A.W., O'Neill, J.P., & McElheny, V.K., ed. Mammalian cell mutagenesis: the maturation of the test  systems, New York, Cold Spring Harbor Laboratory, pp. 237-24 (Banbury Report No. 2).

２４．BAKER, R.M., BRUNETTE, D.M., MANKOVITZ, R., THOMPSON, L.H., WHITMORE, G.F., SIMINOVITCH, L., & TILL, J.E.  (1974)  Ouabain-resistant mutants of mouse and Chinese hamster cells. Cell, 1: 9-21.

２５．BARTSCH, H., CAMUS, A.-M., & MALAVEILLE, C.  (1976)  Comparative mutagenicity of  N-nitrosamines in a semi-solid and liquid incubation system in the presence of rat or human tissue fractions.  Mutat. Res., 37: 149-162.

２６．BARTSCH, H., MALAVEILLE, C., CAMUS, A.-M., MARTEL-PLANCHE, G., BRUN, G., HAUTEFEUILLE, A., SABADIE, N., BARBIN, A.,KUROKI, T., DREVON, C., PICOLLI, C., & MONTESANO, R.  (1979)  Validation and comparative studies on 180 chemicals with  S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolizing systems.  Mutat. Res., 76: 1-50.

２７．BARTSCH, H., MALAVEILLE, C., CAMUS, A.-M., MARTEL-PLANCHE, G., BRUN, G., HAUTEFEUILLE, A., SABADIE, N., BARBIN, A.,KUROKI, T., DREVPM, C., PICCOLI, S., & MONTESANO, R.  (1980)  Bacterial and mammalian mutagenicity tests: validation and comparative studies on 180 chemicals. In: Montesano, R., Bartsch, H., & Tomatis, L., ed.  Molecular and cellular  aspects  of carcinogen screening tests, Lyons, International Agency for Research on Cancer, pp. 179-241 (IARC  Scientific PublicationsNo. 27).

２８．BARTSCH, H., KUROKI, T., ROBERFROID, M., & MALAVEILLE, C.  (1982)  Metabolic activation systems  in vitro for carcinogen-mutagen screening tests. In: de Serres, F.J. & Hollaender, A., ed.  Chemical mutagens, New York, London, Plenum Press, Vol. 7, pp. 95-161.

２９．BATEMAN, A.J.  (1958)  Mutagenic sensitivity of maturing germ cells in the male mouse.  Heredity, 12: 213-232.

３０．BATEMAN, A.J.  (1966)  Testing chemicals for mutagenicity in a mammal.  Nature (Lond.), 210: 205-206.

３１．BATEMAN, A.J. & EPSTEIN, S.S.  (1971)  Dominant lethal mutations in mammals. In: Hollaender, A., ed. Chemical  mutagens: principles and methods for their detection, New York, London, Plenum Press, Vol. 2, pp. 541-568.

３２．BECKER, H.J.  (1966)  Genetic and variegation mosaics in the eye of  Drosophila. Curr. Topics dev. Biol., 1: 155-171.

３３．BENDER, M.A., GRIGGS, H.G., & BEDFORD, J.S.  (1974)  Mechanisms of chromosomal aberration production. III. Chemicals  and ionizing radiation.  Mutat. Res., 23: 197-212.

３４．BOLLER, K. & SCHMID, W.  (1970)  [Chemical mutagenesis in mammals. The bone marrow of the Chinese hamster as an  in vivo test system.]  Haematologische Befunde nach Behandlung mit Trenimon. Humangenetik, 11: 35-54 (in German).

３５．BOYCE, R.P. & HOWARD-FLANDERS, P.  (1964)  Release of ultraviolet light-induced thymine dimers and DNA in  E. coli K-12.  Proc. Natl Acad. Sci. (USA), 51: 293-300.

３６．BOYUM, A.  (1968)  Isolation of mononuclear cells and granulocytes from human blood.  Scand. J. clin. Lab. Invest.,21(Suppl. 97): 77-89.

３７．BRADLEY, M.O., BHUYAN, B., FRANCIS, M.C., LANGENBACH, R., PETERSON, A., & HUMBERMAN, E.  (1981)  Mutagenesis by chemical agents in V79 Chinese hamster cells:   a review and analysis of the literature: a Report of the Gene-tox program.  Mutat. Res., 87: 81-142.

３８．・BRENNEKE, H.  (1937)  [Radiation damage to mouse and rat sperm, observed from the early development of the ova.] Strahlentherapie, 60: 214-238 (in German).

３９．BREWEN, J.G. & PRESTON, R.J.  (1982)  Cytogenic analysis of mammalian oocytes in mutagenicity studies. In: Hsu, T.C., ed. Cytogenic assays of environmental mutagens, New York, Allanheld Osmun & Co., pp. 277-287.

４０．BREWEN, J.G. & STETKA, D.G.  (1982)  Cytogenetic events in vivo. In: Heddle, J.A., ed.  Mutagenicity: new horizons in genetic toxicology, New York, London, Academic Press, pp. 351-384.

４１．BREWEN, J.G., PAYNE, H.S., JONES, K.P., & PRESTON, R.J.  (1975)  Studies on chemically-induced dominant lethality.  I. The cytogenetic basis of MMS-induced dominant lethality in post-meiotic male germ cells.  Mutat. Res., 33: 239-250.

４２．BRIDGES, B.A., CLEMMESEN, J., & SUGIMURA, T.  (1979)  Cigarette smoking - does it carry a genetic risk?  Mutat. Res. 65, 71-81 (ICPEMC Publication No. 3)

４３．BRUCE, W.R. & HEDDLE, J.A.  (1979)  The mutagenic activity of 61 agents as determined by the micronucleus,  Salmonella  and sperm abnormality assays.  Can. J. Genet. Cytol., 21: 319-335.

４４．BRUSICK, D.  (1980)  Genetic risk estimation. In:  Principles  of genetic toxicology, New York, London, Plenum Press, pp. 109-135.

４５．BUCKTON, K.E., JACOBS, P.A., COURT BROWN, W.M., & DOLL, R.  (1962)  A study of the chromsome damage persisting after X-ray therapy for ankylosing spondolitis.  Lancet, 2: 676-682.

４６．BURTON, K.  (1956)  A study of the conditions and the mechanism of the diphenylamine reaction for the colorimetric  estimation of DNA.  Biochem. J., 62: 315-323.

４７．CALLEN, D.F. & PHILPOT, R.M.  (1977)  Cytochrome P-450 and the activation of promutagens in  Saccharomyces cerevisiae. Mutat. Res., 45: 309-324.

４８．CASKEY, C.T. & KRUSH, G.D.  (1979)  The HPRT locus.  Cell, 16: 1-9.

４９．CLAYSON, D.B.  (1981)  Carcinogens and carcinogen enhancers. Mutat. Res., 86: 217-229 (ICPEMC Working Paper No 2/3).

５０．CLEAVER, J.E.  (1982)  DNA damage, DNA repair, and DNA replication in short-term tests for exposure to mutagens. In:Kora, K.C., Douglas, G.R., & Nestmann, E.R., ed.  Mutagenesis, human population monitoring, and genetic risk assessment, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 111-124 (Progress in Mutation Research, Vol. 3).

５１．CLEAVER, J.E. & THOMAS, G.H.  (1981)  Measurement of unscheduled synthesis by autoradiography. In: Friedberg, E.C. & Hanawalt, P.C., ed.  DNA repair: a laboratory manual of  research procedures, New York, Basel, Marcel Dekker, pp. 277-287.

５２．CLIVE, D., FLAMM, W.G., MACHESKI, M.R., & BERNHEIM,N.J.  (1972)  A mutational assay system using the thymidine kinase locus in mouse lymphoma cells.  Mutat. Res., 16: 77-87.

５３．CLIVE, D., JOHNSON, K.O., SPECTOR, J.F.S., BATSON, A.G., & BROWN, M.M.M.  (1979)  Validation and characterization of  the L5178Y TK+/- mouse lymphoma mutagen assay system:  Mutat. Res. 59: 61-108.

５４．CLIVE, D., MCCUEN, R., SPECTOR, J.F.S., PIPER, C., & MAVOURIM, K.H.  (1983)  Report of the Gene-Tox program on L5178Y. Mutat. Res., 115: 225-251.

５５．COLE, J., ARLETT, C.F., LOWE, J., & BRIDGES, B.A.  (1982)  The mutagenic potency of 1,8-dinitropyrene in cultured mouse lymphoma cells.  Mutat. Res., 93: 213-220.

５６．COLE, R.J., TAYLOR, N.A., COLE, J., & ARLETT, C.F.  (1979)  Transplacental effects of chemical mutagens detected by the micronucleus test.  Nature (Lond.), 277: 317-318.

５７．COLE, R.J., TAYLOR, N.A., COLE, J., & ARLETT, C.F.  (1981)  Short-term tests for transplacentally active carcinogens.  I. Micronucleus formation in fetal and maternal mouse  erythroblasts.  Mutat. Res., 80: 141-157.

５８．COLLINS, A.R.S., SHOR, S.L., & JOHNSON, R.T.  (1977)  The inhibition of repair in UV-irradiated human cells.  Mutat. Res., 42: 413-432.

５９．COMBES, R.D., ANDERSON, D., BROOKS, T.M., NEALE, S., & VENITT, S.  (1984)  The detection of mutagens in urine, faeces, and body fluids. In: Dean, B.J., ed.  UKEMS Subcommittee on  Guidelines for Mutagenicity Testing. Part II. Supplementary Tests, Swansea, United Kingdom Environmental Mutagen Society.

６０．CONSTANTIN, M.J.  (1976)  Mutations for chlorophyll-deficiency in barley: comparative effects off physical and chemical mutagens. In:Gaul, H., ed.  Barley genetics. III, Munich, Karl Thiemig.

６１．CONSTANTIN, M.J. & NILAN, R.A.  (1982)  Chromosome aberrations in barley  (Hordeum vulgare): a report of the US Environmental Portection Agency Gene-Tox Program.  Mutat. Res., 99: 13-36.

６２．CONSTANTIN, M.J. & OWENS, E.T.  (1982)  Introduction and perspectives of plant genetic and cytogenetic assays: a report of the US Environmental Protection Agency Gene-Tox Program. Mutat. Res., 99: 1-12.

６３．DARLINGTON, D.C. & LACOUR, L.F.  (1976)   The handling of  chromosomes, 6th ed., London, Allen and Unwin, 201

６４．DAVIES, P.J., TIPPINS, R.S., & PARRY, J.M.  (1978)  Cell-cycle variation in the induction of lethality and mitotic recombination after treatment with UV and nitrous acid in the yeast  Saccharomyces cerevisiae. Mutat. Res., 51: 327-328.

６５．DEAN, B.J.  (1969)  Chemically-induced chromosome damage. Lab. Anim., 3: 157-174.

６６．DEAN, B.J.  (1985)  Summary report on the performance of cytogenetic assays in cultured mammalian cells. In:  Ashby, J.,  de Serres, F.J., Draper, M., Ishidate, M., Jr, Margolin, B., Matter, B., & Shelby, M.D., ed.  Evaluation of short-term  tests for carcinogens, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 69-83 (Progress in Mutation Research,Vol. 5).

６７．DEAN, B.J. & DANFORD, N.D.  (1985)  Assays for the detection of chemically-induced chromosome damage in cultured mammalian cells. In: Venitt, S. & Parry, J.M., ed.  Mutagenicity testing: a practical approach, Oxford, IRL Press, pp. 187-232.

６８．DEAN, B.J. & HODSON-WALKER, G.  (1979)  An  in vitro chromosome assay using cultured rat-liver cells.  Mutat. Res., 64: 329-337.

６９．DEAN, B.J., ANDERSON, D., & SRAM, R.J.  (1981)  Mutagenicity of selected chemicals in the mammalian dominant lethal assay. In: de Serres, F.J. & Shelby, M.D., ed.  Comparative chemical mutagenisis, New York, London, Plenum Press, pp. 487-538.

７０．DEAN, B.J., BRIDGES, B.A., KIRKLAND, D.J., PARRY, J.M., & TAYLOR, N.A.  (1983)  Framework of supplementary testing procedures. In: Dean, B.J., ed.  UKEMS Sub-Committee on  Guidelines for Mutagenicity Testing. Part 1, Swansea, United Kingdom Environmental Mutagen Society.

７１．DEBAUN, J.R., MILLER, E.C., & MILLER, J.A.  (1970)  N-hydroxy-2 acetylaminefluorene sulfotransferase: its probable role in carcinogenesis and in protein (methionyl-S-yl) binding in rat liver.  Cancer Res., 30: 577-595.

７２．DEMEREC, M., & KAUFMAN, B.P.  (1973)   Drosophila guide: introduction to the genetics and cytology of Drosophila Melanogaster, Washington DC, Carnegie Institute of Washington, 45 pp.

７３．DE SERRES, F.J. & ASHBY, J., ed.  (1981)   Evaluation of  short-term tests for carcinogens, Amsterdam, Oxford, New York, Elsevier Science Publishers (Progress in Mutation Research, Vol. 1).

７４．DHSS  (1981)   Guidelines for testing chemicals for  mutagenicity, London, Committee on Mutagenicity of Chemicals in Food, Consumer Products, and the Environment, Department of Health and Social Security (Report on Health and Social Subjects No. 24).

７５．DHSS  (1982)   Guidelines for the testing of chemicals for  mutagenicity. V. Genetic and partly-genetic diseases of man: types, frequencies, and mutation rates, London, UK Department of Health and Social Security (Report on Health and Social Subjects No. 24).

７６．DRAPER, M.H. & GRIFFIN, J.P.  (1980)  Draft guidelines on mutagenicity testing of new drugs issued by the CPMP. A four test screen.  Arch. Toxicol., 46: 9-19.

７７．EHLING, U.H.  (1977)  Dominant lethal mutations in male mice. Arch. Toxicol., 38: 1-11.

７８．EHLING, U.H., CUMMING, R.B., & MALLING, H.V.  (1968)  Induction of dominant lethal mutations by alkylating agents in male mice.  Mutat. Res., 5: 417-428.

７９．EHLING, U.H., MACHEMER, L., BUSELMAIER, W., DYCKA, J., FROHBERG, H., KRATOCHVILOVA, J., LANG, R.,

８０．LORKE, D., MULLER, D.,  PEH, J., ROHRBORN, G., ROLL, R., SCHULZE-SCHENCKING, M., & WIEMANN, H.  (1978)  Standard protocol for the dominant lethal test on male mice.  Arch. Toxicol., 39: 173-185.

８１．EHRENBERG, L.  (1979)  Risk assessment of ethylene oxide and other compounds. In: McElheny, V.K. & Abrahamson, S., ed. Assessing chemical mutagens: the risk to humans, New York, Cold Spring Harbour Laboratories, pp. 157-190 (Banbury Report No. 1).

８２．EPSTEIN, S.S. & SHAFNER, H.  (1968)  Chemical mutagens in the human environment.  Nature (Lond.), 219: 385-387.

８３．EVANS, H.J.  (1962)  Chromosome aberrations induced by ionizing radiation.  Int. Rev. Cytol., 13: 221-321.

８４．EVANS, H.J.  (1976)  Cytological methods for detecting chemical mutagens. In: Hollaender, A., ed.  Chemical mutagens: principles and methods for their detection, New York, London, Plenum Press, Vol. 4, pp. 1-29.

８５．EVANS, H.J. & O'RIORDAN, M.L.  (1975)  Human peripheral blood lymphocytes for the analysis of chromosomal aberrations in mutagen tests.  Mutat. Res., 31: 135-148.

８６．EVANS, H.J. & SCOTT, D.  (1964)  Influence of DNA synthesis on the production of chromatid aberrations by X-rays and maleic hydrazide in  Vicia faba. Genetics, 49: 17-38.

８７．FAHRIG, R.  (1975)  Development of host-mediated mutagenicity tests: yeast systems. Recovery of yeast cells out of  testes, liver, lung, and peritoneum of rats.  Mutat. Res., 31: 381-394.

８８．FAHRIG, R.  (1977)  The mammalian spot test with mice.  Arch. Toxikol., 38: 87-98.

８９．FEDERAL REGISTER  (1978)  Non-clinical laboratory studies: good laboratory practice regulations.  Fed. Reg., 43(247): 59986-60025.

９０．FEDERAL REGISTER  (1983)  Toxic substances control: good laboratory practice standards.  Fed. Reg., 48(230): 53922-53969.

９１．FINK, G.R. & LOWENSTEIN, R.  (1971)  Simplified method for testing mutagens in  Saccharomyces. J. Bacteriol., 100: 1126-1127.

９２．FISCHER, G.A., LEE, S.Y., & CALABRESI, P.  (1974)  Detectionof chemical mutagens using a host-mediated assay (L5178Y)  mutagenesis system.  Mutat. Res., 26: 501-511.

９３．FOX, M.  (1981)  Some quantitative aspects of the response of mammalian cells  in vitro to induced mutagenesis. In: Marchalonis, J.J. & Hanna, M.G., ed.  Cancer Biology Review, New York, Basel, Marcel Decker Inc, Vol. 3, pp. 23-62.

９４．GARCIA-BELLIDO, A., RIPOLL, P., & MORATA, G.  (1976)  Developmental compartmentalization in the dorsal mesothatic disc of  Drosophila. Dev. Biol., 48: 132-147.

９５．GARNER, R.C., MILLER, E.C., MILLER, J.A., GARNER J.V., & HANSON, R.S.  (1971)  Formation of a factor lethal for S. typhimurium TA 1530 and TA 1531 on incubation of aflatoxin B1 with rat liver microsomes.  Biochem. biophys. Res. Commun., 45: 774.

９６．GENOROSO, W.M.  (1969)  Chemical induction of dominant lethals in female mice.  Genetics, 61: 461-470.

９７．GENOROSO, W.M., CAIN, K.T., KRISHNA, M., & HUFF, S.W.  (1979)  Genetic lesions induced by chemicals in spermatozoa and spermatids of mice are repaired in the egg.  Proc. Natl. Acad. Sci. (USA), 76: 435-437.

９８．GOCKE, E., ECKHARDT, K., KING, M.-T., & WILD, D.  (1982)  Some statistical aspects of spontaneous lethal mutations in Drosophila. Mutat. Res., 104: 239-242.

９９．GRAF, U., JUON, H., KATZ, A.J., FREI, J.J., & WURGLER, G.E.  (1983)  A pilot study on a new Drosophila spot test.  Mutat. Res. Lett., 120: 233-239.

１００．GRAFE, A. & VOLLMAR, J.  (1977)  Small numbers in mutagenicity tests.  Arch. Toxicol., 38: 27-34.

１０１．GRANT, W.F.  (1982)  Chromosome aberration assays in Allum: a report of the US Environmental Protection Agency Gene-Tox Program.  Mutat. Res., 99: 273-291.

１０２．GRIESEMER, R.A. & CUETO, C., Jr  (1980)   Toward a  classification scheme for degrees of experimental evidence for  the carcinogenicity of chemicals for animals. In: Montesano, R., Bartsch, H., & Tomatis, L., ed.  Molecular and cellular  aspects of carcinogen screening tests, Lyons, International Agency for Research on Cancer, pp. 259-281 (IARC Scientific Publication No. 27).

１０３．GUPTA, R.A. & SINGH, B.  (1982)  Mutagenic responses of five independent genetic loci in CHO cells to a variety of mutagens: development and characteristics of a mutagen screening system based on selection for multiple drug-resistan markers.  Mutat. Res., 94: 449-466.

１０４．HANAWALT, P.C., COOPER, P.K., GANESAN, A.K., & SMITH, C.A.  (1979)  DNA repair in bacteria and mammalian cells. Ann. Rev. Biochem., 48: 783-836.

１０５．HASEMAN, J.K. & SOARES, E.R.  (1976)  The distribution of fetal death in control mice and its implications on statistical tests for dominant lethal effects.  Mutat. Res., 41: 277-288.

１０６．HEDDLE, J.  (1973)  A rapid  in vivo test for chromosomal damage.  Mutat. Res., 18: 187-190.

１０７．HEDDLE, J.A. & CARRANO, A.V.  (1977)  The DNA content of micronuclei induced in mouse bone marrow by y-irradiation: evidence that micronuclei arise from acentric chromosomal fragements.  Mutat. Res., 44: 63-69

１０８．HEDDLE, J.A., BLAKEY, D.H., DUNCAN, A.M.V., GOLDBERG, M.T., NEWMARK, H., WARGOVICH, M.J., & BRUCE, W.R.  (1982)  Micronuclei and related anomalies as a short-term assay for colon carcinogens. In: Bridges, B.A., Butterworth, B.E., & Weinstein, I.B., ed.  Indicators of genotoxic exposure, New York, Cold Spring Harbor Laboratory, pp. 367-375 (Banbury Report No. 13).

１０９．HERTWIG, P.  (1935)  [Sterility phenomena in mice irradiated with X-rays.]  Z. indukt. Abstamm. - u. VererbLehre,  70: 517-523 (in German).

１１０．HOLSTEIN, N., MCCANN, J., ANGELOSANTO, F.A., & NICHOLS, W.W.  (1979)  Short-term tests for carcinogens and mutagens. Mutat. Res., 64: 133-226.

１１１．HOZIER, J., SAWYER, J., MOORE, M., HOWARD, B., & CLIVE, D.  (1981)  Cytogenic analysis of the L5187Y TK+1- TK1 mouse  lymphoma mutagenesis assay system.  Mutat. Res., 84: 167-181.

１１２．HSIE, A.W., O'NEILL, J.P., & MCELHENY, V.K., ed.  (1979)  Mammalian cell mutagenesis: the maturation of test systems, New York, Cold Spring Harbor Laboratory (Banbury Report No. 2).

１１３．HSIE, A.W., CASCIANO, D.A., CROUCH, D.B., KRAHN, D.F., O'NEILL, J.P., & WHITFIELD, B.L.  (1981)  The use of Chinesehamster ovary cells to quantity specific locus mutation and to determine mutagenicity of chemicals, A report of the  Gene-tox program.  Mutat. Res., 86: 193-214.

１１４．IARC  (1979)   Chemicals and industrial processes associated  with cancer in humans, Lyons, International Agency for Research on Cancer (IARC Monographs Supplement No. 1).

１１５．IARC  (1980a)  Mutagenesis assays with bacteria. In:  Long-term  and short-term screening assays for carcinogens: a critical  appraisal, Lyons, International Agency for Research on Cancer, pp. 85-106 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Supplement 2).

１１６．IARC  (1980b)  In: Castegnaro, M., Hunt, D.C., Sansone, E.B., Schuller, P.L., Siriwardana, M.G., Telling, G.M., van Egmond, H.P., & Walker, E.A., ed.  Laboratory decontamination and  destruction of aflatoxins B1, B2, G1, G2,  in laboratory wastes, Lyons, International Agency for Research on Cancer (IARC Scientific Publications No. 37).

１１７．ICPEMC  (1982)  Mutagenesis testing as an approach to carcinogenesis (Committee 2 Report).  Mutat. Res., 99: 73-91.

１１８．ICPEMC  (1983a)  Screening strategy for chemicals that are potential germ cell mutagens in mammals (Committee 1 Report). Mutat. Res., 114: 117-117.

１１９．ICPEMC  (1983b)  Regulatory approaches to the control of environmental mutagens and carcinogens (Committee 3 Report). Mutat. Res., 114: 179-216.

１２０．ICPEMC  (1983c)  Estimation of genetic risk and increased incidence of genetic disease due to environmental mutagens (Committee 4 Report).  Mutat. Res., 115: 255-291.

１２１．ICPEMC  (1983d)  Estimation of genetic risk and increased incidence due to environmental mutagens (Committee 4 Report) Mutat. Res., 115: 255-291.

１２２．IRR, J.D. & SNEE, R.D.  (1982)  A statistical method for analysis of mouse lymphoma L5178Y cell TK locus forward mutatio assay: comparison of results among three laboratories.  Mutat. Res., 97: 371-392.

１２３．ISCN  (1978)   Original Article Series 14(8), Basel, S. Karger AG, International System for Human Cytogenetic Nomenclature Birth Defects (Also in:  Cytogenet. Cell Genet., 21 309-404). 

１２４．ISHIDATE, M., Jr  (1981)  Application of chromosomal aberration tests  in vitro to the primary screening for chemicals with carcinogenic and/or genetic hazards. In: Short-terms tests for carcinogens: quo vadis? In:  Proceedings of a  Symposium held at Montpelier, France (Excerpta Medica),  pp. 58-59.

１２５．ISHIDATE, M., Jr & ODASHIMA, S.  (1977)  Chromosome tests with 134 compounds in Chinese hamster cells  in vitro:  a screening test for chemical carcinogens.  Mutat. Res., 48: 337-354.

１２６．JENSSEN, D. & RAMEL, C.  (1978)  Factors affecting the induction of micronuclei at low doses of X-rays, MMS, and dimethylnitrosamine in mouse erhythroblasts.  Mutat. Res., 58: 51-65

１２７．JOHNSON, R.T. & RAO, P.N.  (1970)  Mammalian cell fusion: introduction of premature chromosome condensation in interphase myclei.  Nature (Lond.), 226: 717-722.

１２８．KAPLAN, W.D. & LYON, M.F.  (1953)  Failure of mercaptoethylamine to protect against the mutagenic effects of radiation.  II. Experiments with mice.  Science, 118: 777-778.

１２９．KASTENBAUM, M.A. & BOWMAN, K.O.  (1970)  Tables for determining the statistical significance of mutation frequencies.  Mutat. Res., 9: 527-549.

１３０．KATZ, A.J.  (1978)  Design and analysis of experiments on mutagenicity. I. Minimal sample size.  Mutat. Res., 50: 301-307.

１３１．KELLY, D. & PARRY, J.M.  (1983a)  Metabolic activation by cytochrome P-450/P-448 in the yeast Saccharomyces cerevisiae. Mutat. Res., 108: 147-158.

１３２．KELLY, S.L. & PARRY, J.M.  (1983b)  The induction of mutation and recombination following UV irradiaion during meiosis in  Saccharoymces cerevisiae. Mutat. Res., 108: 109-120.

１３３．KIHLMAN, B.A.  (1971)  Root-tips for studying the effects of chemicals on chromosomes. In: Hollaender, A., ed.  Chemical  mutagens, New York, London, Plenum Press, Vol. 2, pp. 489-514.

１２４．KIHLMAN, B.A. & ANDERSSON, H.C.  (1982)  Sister chromatid exchanges in plants. In: Wolff, S., ed. Sister chromatid exchange, New York, John Wiley and Sons, pp. 243-265.

１２５．KIRKLAND, D.J., GATEHOUSE, D.G., SULLMAN, S.L., VENITT, S., & WATKINS, P.  (1984)  Bacterial mutation assays with nitrosation products. In: Dean, B.J., ed.  UKEMS Sub-Committee  on Guidelines for Mutagenicity Testing. Part II.  Supplementary  Tests, Swansea, United Kingdom Environmental Mutagen Society.

１２６．KLASTERSKA, I., NATARAJAN, A.T., & RAMEL, C.  (1976)  An interpretation of the origin of subchromatid aberrations and chromosome stickiness as a category of chromatid aberrations. Hereditas, 83: 153-162.

１２７．KLEWOSKI, E.J., Jr  (1978)  Detection of mutational damage in fern populations: an  in situ bioassay for mutagens in aquatic ecosytems. In: Hollaender, A. & de Serres, F.J., ed.  Chemical  mutagens, New York, London, Plenum Press, Vol. 5, pp. 77-99. 

１２８．KLIESCH, U. & ADLER, I.-D.  (1983)  Chromosome analysis and micronucleus test in mouse bone marrow are not equally sensitive as shown by results with 5 chemical mutagens.  Mutat. Res., 113: 340-346.

１２９．KLIESCH, U., ROUPOVA, I., & ADLER, I.-D.  (1982)  Induction of chromosome damage in mouse bone marrow by benzo(a)pyrene. Mutat. Res., 102: 265-273.

１３０．KNUDSON, I.  (1982)  Natural, processed, and artificial mutagens in food: significance and consequences. In: Sorsa, M. & Vainio, H., ed.  Mutagens in our environment, New York, Alan R. Liss, pp 315-328.

１３１．KRATOCHVILOVA, J.  (1978)  Evaluation of pre-implantation loss in dominant-lethal assay in the mouse.  Mutat. Res., 54:  47-54.

１３２．KRUSKAL, W.H. & WALLIS, W.A.  (1952)  Use of ranks in one-criterion variance analysis.  J. Am. Stat. Assoc., 47: 583-621.

１３３．KUNZ, B.A., BARCLAY, B.J., & HAYNES, R.H.  (1980)  A simple, rapid-plate assay for mitotic recombination.  Mutat. Res., 73: 215-220.

１３４．KUROKI, T., DREVON, C., & MONTESANO, R.  (1977)  Microsome- mediated mutagenesis in V79 Chinese hamster cells by various nitrosamines.  Cancer Res., 37: 1044-1050.

１３５．KUROKI, T., MALLAVEILLE, C., DREVON, C., PICCOLI, C., MACLEOD, M., & SELKIRK, J.K.  (1979)  Critical importance of  microsome concentration in mutagenesis assays with V79 Chinese hamster cells.  Mutat. Res., 63: 259-272.

１３６．KURTEN, S. & OBE, G.  (1975)  Premature chromosome condensation in the bone marrow of Chinese hamsters after application  of bleomycin  in vivo. Mutat. Res., 27: 285-294.

１３７．LAHDETIE, J. & PARVINEN, M.  (1981)  Meiotic micronuclei induced by X-rays in early spermatids of the rat.  Mutat.  Res., 81: 103-105.

１３８．LANGENBACH, R., NESNOW, S., TOMPA, A., GINGELL, R., & KUSZYNSKI, C.  (1981)  Lung and liver cell-mediated mutagenesis systems: specificities in the activation of chemical carcinogens.  Carcinogenesis, 2: 852-858.

１３９．LATT, S.A., ALLEN, J.W., ROGERS, W.E., & JUERGENS, L.A.  (1977)   In vitro and  in vivo analysis of sister chromatid  exchange formation. In: Kilbey, B.J., ed.  Handbook of mutagen  testing, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 275-291.

１４０．LATT, S.A., ALLEN, J., BLOOM, S.E., CARRANO, A., FALKE, E., KRAM, D., SCHNEIDERM, E., SCHRECK, R., RICE, R., WHITFIELD, B., & WOLFF, S.  (1981)  Sister-chromatid exchanges: a report of the Gene-Tox Programme.  Mutat. Res., 87: 17-62.

１４１．LEE, W.R., ABRAHAMSON, S., VALENCIA, R., VON HALLE, E.S., WURGLER, F.E., & ZIMMERING, S.  (1983)  The sex-linked recessive lethal test for mutagenesis in  Drosophila  melanogaster:  a report of the US EPA Gene-Tox Program. Mutat. Res., 123: 183-279.

１４２．LEIBER, M., SMITH, B., SZAKAL, A., NELSON-REES, W., & TODARO, G.  (1976)  A continuous tumour-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells.  Int. J. Cancer, 17: 62-70.

１４３．LEVIN, D.E., HOLLSTEIN, M., CHRISTMAN, M.F., SCHWIERS, E.A., & AMES, B.N.  (1982)  A new  Salmonella tester strain (TA102) with A.T base pairs at the site of mutation detects oxidative mutagens.  Proc. Natl Acad. Sci. (USA), 79: 7445-7449.

１４４．LINDSLEY, D.L. & GRELL, E.H.  (1968)   Genetic variations of  Drosophila melanogaster, Washington DC, Carnegie Institute of Washington, 472 pp (Publication No. 627).LONAIT-GALLIGANO, M., LOHMAN, P.H.M., & BERENDS, F.  (1983)  The validity of the autoradiographic method for detecting DNA repair synthesis in rat hepatocyte primary culture.  Mutat. Res., 113: 145-160.

１４５．LOPRIENO, N.  (1981)  Screening of coded carcinogenic non-carcinogenic chemicals by a forward mutation system with the yeast  Schizosaccharomyces pombe.  In: de Serres, F.J. & Ashby, J., ed.  Evaluation of short-term tests for carcinogens,  Amsterdam,Oxford, New York, Elsevier Science Publishers (Progress in Mutation Research, Vol. 1).

１４６．LOPRIENO, N., ABBONDANDOLO, A., BARALE, R., BARONCELLI, S., BONATTI, S., BRONZETTI, G., CAMMELLINI, A., CORSI, C., CORTI, G., FREZZA, D., LEPORINI, C., MAZZACCARO, A., NIERI, R., ROSELLINI, D., & ROSSI, A.M.  (1976)  Mutagenicity of  industrial compounds: styrene and its possible metabolite styrene oxide.  Mutat. Res., 40: 317-324.

１４７．LOPRIENO, N., BARALE, R., VON HALLE, E.S., & VON BORSTEL, R.C.  (1983)  Testing of chemicals for mutagenic activity  with  Schizosaccharomyces pombe:  a report of the US Environmental Protection Agency Gene-Tox Program.  Mutat. Res., 115: 215-233.

１４８．MA, T.H.  (1982a)   Tradescantia cytogenetic tests (root-tip mitotis, pollen mitosis, pollen mother-cell meiosis): a report of the US Environmental Protection Agency Gene-Tox Program. Mutat. Res., 99: 293-302.

１４９．MA, T.H.  (1982b)   Vicia cytogenetic test for environmental mutagens: a report of the US Environmental Protection Agency Gene-Tox Program.  Mutat. Res., 99: 257-271.

１５０．MCCANN, J. & AMES, B.N.  (1976)  Detection of carcinogens as mutagens in the  Salmonella/microsome test: assay of 300 chemicals: discussion.  Proc. Natl Acad. Sci. (USA), 73: 950-954.

１５１．MCCANN, J.E., CHOI, E., YAMASAKI, E., & AMES, B.N.  (1975)  Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.  Proc. Natl  Acad. Sci. (USA), 72: 5135-5139.

１５２．MACKEY, B.E. & MACGREGOR, J.T.  (1979)  The micronucleus test: statistical design and analysis.  Mutat. Res., 64: 195-204.

１５３．MCMAHON, R.E., CLINE, J.C., & THOMPSON, C.Z.  (1979) Assay of 855 test chemicals in ten tester strains using a new modification of the Ames test for bacterial mutagens.  Cancer  Res., 39: 682-693.

１５４．MALLING, H.V.  (1971)  Dimethylnitrosamine: formation of mutagenic compounds by interaction with mouse liver microsomes.  Mutat. Res., 13: 425-429.

１５５．MANN, H.B. & WHITNEY, D.R.  (1947)  On a test of whether one of two random variables is stochastically larger than the other.  Ann. Math. Stat., 18: 50-60.

１５６．MARON, C. & AMES, B.N.  (1984)  Revised methods for the  Salmonella mutagenicity test. In: Kilbey, B.J., Legator, M., Nichols, W., & Ramel, C., ed.  Handbook of mutagenicity test  procedures, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 93-141.

１５７．MARON, D., KATZENELLENBOGEN, J., & AMES, B.N.  (1981)  Comparability of organic solvents with the  Salmonella/microsome test.  Mutat. Res., 88: 343-350.

１５８．MARTIN, C.N., MCDERMID, A.C., & GARNER, R.C.  (1978)  Testing of known carcinogens and non-carcinogens for their ability to induce unscheduled DNA synthesis in HeLa Cells.  Cancer Res., 38: 2621-2627.

１５９．MATSUSHIMA, T., TAKAMOTO, Y., SHIVAI, A., & SUGIMURA, T.  (1981)  Reverse mutation test on H2-coded compounds with the  E. coli WP2 system. In: de Serres, F.J. & Ashby, J., ed. Evalutation of short-term tests for carcinogens, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 287-395 (Progress in Mutation Research, Vol. 1).

１６０．MATTER, B. & SCHMID, W.  (1971)  Trenimon-induced chromosomal damage in bone-marrow cells of six mammalian species, evaluated by the micronucleus test.  Mutat. Res., 12: 417-425.

１６１．MEHTA, R.D. & VON BORSTEL, R.C.  (1981)  Mutagenic activity of 42 encoded compounds in the haploid reversion assay strain XV185-14C. In: de Serres, F.J. & Ashby, J., ed.  Evaluation of  short-term tests for carcinogens, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 414-423 (Progress in Mutation Research, Vol. 1).

１６２．MEYER, A.L.  (1983)   In vitro transformation assays for chemical carcinogens.  Mutat. Res., 115: 323-338.

１６３．MILLER, E.C. & MILLER, J.A.  (1966)  Mechanisms of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules.  Pharmacol. Rev., 18: 805-838.

１６４．MILLER, E.C. & MILLER, J.A.  (1971)  The mutagenicity of chemical carcinogens: correlations, problems, and interpretation. In: Hollaender, A., ed.  Chemical mutagens: principles and methods for their detection, New York, London, Plenum Press, pp. 83-119.

１６５．MIRSALIS, J.C. & BUTTERWORTH, B.E.  (1980)  Detection of unscheduled DNA synthesis in hepatocytes from rats treated with genotoxic agents: an  in vivo - in vitro assay for potential carcinogens and mutagens.  Carcinogenesis, 1: 621-625.

１６６．MITCHELL, A.D., CASCIANO, D.A., MELTZ, M.L., ROBINSON, D.E., SAN, R.H.C., WILLIAMS, G.M., & VON HALLE, E.S.  (1983)  Unscheduled DNA synthesis tests: a report of the US Environmental Protection Agency Gene-Tox Program.  Mutat. Res., 123: 363-410.

１６７．MITELMAN, F.  (1983)  Catalogue of chromosome aberrations in cancer.  Cytogenet. cell Genet., 36: Nos. 1-2.

１６８．MONTESANO, R., BARTSCH, H., BOYLAND, E., DELLA PORTA, G., FISHBEIN, L., GREISEMER, R.A., SWAN, A.B., & TOMATIS, L., ed.  (1979)   Handling chemical carcinogens in the laboratory: problems of safety, Lyons, International Agency for Research on Cancer (IARC Scientific Publications No. 33).

１６９．MRC  (1981)   Guidelines for work with chemical carcinogens in  Medical Research Council establishments, London, Medical Research Council.

１７０．NCI  (1981)   Safety standards for research involving chemical  carcinogens, National Cancer Institute, US Department of Health, Education and Welfare (US DHEW Publication No. (NIH) 76-900).

１７１．NEEL, J.V. & SCHULL, W.J.  (1958)   Human heredity, Chicago, The University of Chicago Press.OAKBERG, E.F.  (1960)  Irradiation damage to animals and its effect on their reproductive capacity.  J. dairy Sci., 43(Suppl.): 54-67.

１７２．OBE, G., NATARAJAN, A.T., & PALITTI, F.  (1982)  Role of DNA double-strand breaks in the formation of radiation-induced chromosomal aberrations. In: Natarajan, A.T., Obe, G., & Altmann, H., ed.  DNA repair, chromosome alterations and  chromatin structure, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 1-9 (Progress in Mutation Research, Vol. 4). OECD  (1982a)   Good laboratory practice in the testing of  chemicals, Paris, Organisation for Economic Cooperation and Development (ISBN 92-64-12367-9).

１７３．OECD  (1982b)   Decision of the Council concerning the minimum  premarketing set of data in the assessment of chemicals, Paris, Organisation for Economic Cooperation and Development.

１７４．OECD  (1984)   Data interpretation guides for initial hazard  assessment of chemicals (provisional), Paris, Organisation for Economic Cooperation and Development, pp. 58-60.

１７５．PARRY, J.M. & PARRY, E.M.  (1983)  The detection of induced chromosome aneuploidy using strains of the yeast  Saccharomyces  cerevisiae.  In: Kilbey, B.J., ed.  Handbook of mutagenicity  test procedures, Amsterdam, Oxford, New York, Elsevier Science Publishers, Vol. 2.

１７６．PARRY, J.M. & SHARP, D.C.  (1981)  Induction of mitotic aneuploidy in the yeast strain D6 by 42 coded compounds. In: de Serres, F.J. & Ashby, J., ed.  Evaluation of short-term  tests for carcinogens, Amsterdam, Oxford, New York Elsevier Science Publishers, pp. 468-480 (Progress in Mutation Research, Vol. 1).

１７７．PARRY, J.M. & WILCOX, P.  (1982)  The genetic toxicology in fungi of 4CMB, 4HMB, and BC. Survey of the results of the UKEMS collaborative genotoxicity trial 1981.  Mutat. Res., 100: 185-200

１７８．PARRY, J.M. & ZIMMERMANN, F.K.  (1976)  The detection of monosomic colonies produced by mitotic non-disjunction in the yeast  Saccharomyces cerevisiae. Mutat. Res., 36: 49-66.

１７９．PARRY, J.M., TWEATS, D.J., & AL-MOSSAWI, M.A.J.  (1976)  Monitoring the marine environment for mutagens.  Nature  (Lond.) 264: 538-540.

１８０．PARRY, J.M., PARRY, E.M., & BARRETT, J.C.  (1980)  Tumour promotors induce mitotic aneuploidy in yeast.  Nature (Lond.),  294: 263-265.

１８１．PERRY, P.E.  (1980)  Chemical mutagens and sister-chromatid exchange. In: de Serres, F.J. & Hollaender, A., ed.  Chemical mutagens: principles and methods for their detection,  New York, London, Plenum Press, Vol. 6, pp. 1-39.

１８２．PERRY, P.E. & THOMSON, E.J.  (1984)  Sister-chromatid exchange methodology. In: Kilbey, B.J., et al., ed.  Handbook of mutagenicity test procedures, 2nd ed., Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 495-529.

１８３．PERRY, P.E. & WOLFF, S.  (1974)  New Giemsa method for the differential staining of sister chromatids.  Nature (Lond.),251: 156-158.

１８４．PLEWA, M.J.  (1982)  Specific-locus mutation assays in  Zea  mays:  a report of the US Environmental Protection Agency Gene-Tox Program.  Mutat. Res., 99: 317-377.

１８５．PMAA  (1976)   Current good laboratory practices in drug safety  evaluation in laboratory animals: guidelines, Washington DC, Pharmaceutical Manufacturers Association of America.

１８６．PRESTO, R.J., AU, W., BENDER, M.A., BREWEN, J.G., CARRANO, A.V., HEDDLE, J.A., MCFEE, A.F., WOLFF, S., & WASSOM, J.S.  (1981) Mammalian  in vivo and  in vitro cytogenetic assays: a report of the US EPA's Gene-Tox Program.  Mutat. Res., 87: 143-188.

１８７．PURCHASE, I.F.H., LONGSTAFF, E., ASHBY, J., STYLES, J.A., ANDERSON, D., LEFEVRE P.A., & WESTWOOD, F.R.  (1978)  An evaluation of six short-term tests for detecting organic chemical carcinogens.  Br. J. Cancer, 37: 873-959.

１８８．RASSMUSEN, R.E. & PAINTER, R.B.  (1964)  Evidence for repair of ultraviolet damaged deoxyribonucleic acid in cultured mammalian cells.  Nature (Lond.), 203: 1360-1362.

１８９．READ, J.  (1959)   Radiation biology of Vicia Faba in relation  to the general problem, Springfield, Illinois, Charles C. Thomas.

１９０．REGAN, J.D. & SETLOW, R.B.  (1974)  Two forms of repair in the DNA of human cells damaged by chemical carcinogens and mutagens.  Cancer Res., 34: 3318-3325.

１９１．REVELL, S.H.  (1959)  The accurate estimation of chromatid breakage and its relevance to a new interpretation of chromatid aberrations induced by ionizing radiation.  Proc. Royal Soc. Lond. Ser. B, 150: 563-589.

１９２．RINKUS, S.J. & LEGATOR, M.S.  (1979)  Chemical characterization of 465 known or suspected chemical carcinogens and their correlation with mutagenic activity in the  Salmonella typhimurium system.  Cancer Res., 39: 3289-3318.

１９３．ROWLAND, I.R., RUBERY, E.D., & WALKER, R.  (1984)  Bacterial assays for mutagens in food. In: Dean, B.J., ed.  UKEMS  Sub-Committee on Guidelines for Mutagenicity Testing. Part II. Supplementary Tests, Swansea, United Kingdom Environmental Mutagen Society.

１９４．RUSSELL, L.B.  (1962)  Chromosome aberrations in experimental mammals. In: Steinberg, A.G. & Bearn, A.G., ed.  Progress in  medical genetics, New York, London, Grune and Stratton, Vol. 2, pp. 230-294.

１９５．RUSSELL, L.B.  (1978)  Somatic cells as indicators of germinal mutations in the mouse.  Environ. Health Perspect., 24: 113-116.

１９６．RUSSELL, L.B. & RUSSELL, W.L.  (1956)  The sensitivity of different stages in oogenesis to the radiation induction of dominant lethals and other changes in the mouse. In: Mitchell, J.S., Holmes, B.E., & Smith, C.L., ed.  Progress in radiobiology, Edinburgh, Oliver and Boyd, pp. 187-192.

１９７．RUSSELL, W.L., RUSSELL, L.B., & KIMBALL, A.W.  (1954)  The relative effectiveness of neutrons from a nuclear detonation and from a cyclotron in inducing dominant lethals in the mouse.  Am. Nat., 88: 269-286. 

１９８．RUSSELL, W.C., NEWMAN, C., & WILLIAMSON, D.H.  (1975)  A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses.  Nature (Lond.), 253: 461-462.

１９９．SALAMONE, M., HEDDLE, J., STUART, E., & KATZ, M.  (1980)  Towards an improved micronucleus test. Studies on 3 model agents mitomycin C, cyclophosphamide, and dimethylbenzanthracene. Mutat. Res., 74: 347-356.

２００．SAN, R.H.C. & STICH, H.F.  (1975)  DNA repair synthesis of cultured human cells as a rapid bioassay for chemical carcinogens.  Int. J. Cancer, 16: 284-291.

２０１．SANKARANARAYANAN, K.  (1982)  Determination and evaluation of genetic risk to humans from exposure to chemicals. In: Bora, K.C., Douglas, G.R., & Nestmann, E.R., ed.  Chemical  mutagenesis, human population monitoring and genetic risk  assessment, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 289-321 (Progress in Mutation Research, Vol. 3).

２０２．SAVAGE, J.R.K.  (1976)  Annotation: Classification and relationships of induced chromosomal structural changes. J. med. Genet., 13: 103-122.

２０３．SAX, K.  (1938)  Chromosome aberrations induced by X-rays. Genetics, 23: 494-516.

２０４．SCHAEFER, H.  (1939)  [The fertility of male mice after irradiation with 200r.]  Z. mikrosk. -anat. Forsch., 46: 121-152 (in German).

２０５．SCHAIRER, L.A., VAN'T HOF, J., HAYES, C.G., BURTON, R.M., & DE SERRES, F.J.  (1978)  Exploratory monitoring of air pollutants for mutagenic activity with the  Tradescantia stamen hair system. Environ. Health Perspect., 27: 51-66.

２０６．SCHMID, W.  (1976)  The micronucleus test for cytogenetic analysis. In: Hollaender, A., ed.  Chemical mutagens: principles and methods for their detection, New York, London, Plenum Press, Vol. 4, pp. 31-53.

２０７．SCHMID, W., ARAKAKI, D.T., BRESLAU, N.A., & CULBERTSON, H.C.  (1971)  Chemical mutagenesis. The Chinese hamster bone marrow as an  in vivo test system. I. Cytogenetic results on basic aspects of the methodology, obtained with alkylating agents. Humangenetik, 11: 103-118.

２０８．SCHMIDT, G. & THANNHAUSER, S.  (1945)  A method for the determination of deoxyribonucleic acid, ribonmucleic acid, and phosphoproteins in animal tissues.  J. Biol. Chem., 161: 83-89.

２０９．SCOTT, D., DANFORD, N.D., DEAN, B.J., KIRLAND, D., & RICHARDSON, C.R.  (1983)  Chromosome aberration assays in mammalian cells  in vitro.  In: Dean, B.J., ed.  Report of the  UKEMS Sub-Committee on Guidelines for Mutagenicity Testing, Swansea, United Kingdom Environmental Mutagen Society, pp. 43-64.

２１０．SEARLE, A.G.  (1975)  The specific locus test in the mouse. Mutat. Res., 31: 277-290.

２１２．SEARLE, A.G. & BEECHEY, C.V.  (1974)  Sperm-count, egg-fertilization, and dominant lethality after X-irradiation of mice.  Mutat. Res., 22: 63-72.

２１３．SETCHELL, B.P.  (1970)  Testicular blood supply, lymphatic drainage, and secretion of fluid. In: Johnson, A.D., Gomes, W.R., & VanDemark, N.L., ed.  The testis, New York, London, Academic Press, Vol. 1, pp. 101-239.

２１４．SETLOW, R.B. & CARRIER, W.L.  (1964)  The disappearance of thymine dimers from DNA: an error correcting mechanism.  Proc. Natl Acad. Sci. (USA), 51: 226-231.

２１５．SHARP, D.C. & PARRY, J.M.  (1981)  Induction of mitotic gene conversion by 41 coded compounds using the yeast culture JD1. In: de Serres, F.J. & Ashby, J., ed.  Evaluation of short-term  tests for carcinogens, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 491-501 (Progress in Mutation Research, Vol. 1).

２１６．SIMINOVITCH  (1976)  On the nature of hereditable variation in cultured somatic cells.  Cells, 7: 1-11.

２１７．SIRIANNI, S.R., FURUKAWA, M., & HUANG, C.C.  (1979)  Induction of 8-azagucnine and ouabina-resistant mutants by cyclophosphamide and 1-(pyridyl-3)-3, d-dimehytyltriazie in Chinese hamster cells cultured in diffusion chambers in mice. Mutat. Res., 64: 259-267.

２１８．SNEDECOR, G.W. & COCHRAN, W.G.  (1967)   Statistical methods, 6th ed., Ames, Iowa State University Press, pp. 240-242.

２１９．SNEE, R.D. & IRR, J.D.  (1981)  Design of a statistical method for the analysis of mutagenesis at the hypocanthine-guanine phosphoribosyl transferase locus of cultured Chinese hamster ovary cells.  Mutat. Res., 85: 77-93

２２０．SOKAL, R.R. & ROHLF, F.J.  (1969)   Biometry, San Franciso, California, W.H. Freeman and Co.

２２１．SORA, S., LUCCHINI, G., & MAGNI, G.E.  (1982)  Meiotic diploid progeny and meiotic non-disjunction in  Saccharomyces  cerevisiae. Genetics, 101: 17-33.

２２２．STADLER, L.J.  (1932)  On the genetic nature of induced mutations in plants.  Proc. VI Int. Congr. Genet., 1: 274-294.

２２３．SULOVKSA, K., LINDEGREN, D., ERIKSSON, G., & EHRENBERG, L.  (1969)  The mutagenic effect of low concentrations of ethylene oxide in air.  Hereditas, 62: 264.

２２４．TAN, E.-L. & HSIE, A.W.  (1981)  Mutagenicity and cytotoxicity of haloethanes as studied in the CHO/HGPRT system.  Mutat. Res., 90: 183-191.

２２５．TATES, A.D., NEUTEBOOM, I., HOFKER, M. & DEN ENGELSE, L.  (1980)  A micronucleus technique for detecting clastogenic effects of mutagens/carcinogens (DEN, DMN) in hepatocytes of rats  in vivo. Mutat. Res., 74: 11-20.

２２６．THOMPSON, L.H. & BAKER, R.M.  (1973)  Isolation of mutants of cultured mammalian cells. In: Prescott, D.M., ed.  Methods in  cell biology. IV, New York,London, Academic Press, pp. 209-28.

２２７．TJIO, J.H. & WHANG, J.  (1965)  Direct chromosome preparations of bone marrow cells. In: Yunis, J., ed.  Human chromosome  methodology, New York, London, Academic Press, pp. 51-56.

２２８．TOMKINS, D.J. & GRANT, W.F.  (1976)  Monitoring natural vegitation for herbicide-induced chromosomal aberrations. Mutat. Res., 36: 73-84.

２２９．UNIVERSITY OF BIRMINGHAM  (1980)   Rules and notes of guidance  for the use of chemical carcinogens in the university, Birmingham, The University of Birmingham.

２３０．US EPA  (1976)   An ordering of the NIOSH suspected carcinogens list based only on data contained in the list BP-251851, Washington DC, US Environmental Protection Agency.

２３１．US FDA  (1979)   GLP regulations: management briefings, Washington DC, US Food and Drug Administration (Post-conference Report).

２３２．US FDA  (1982)   GLP regulations: questions and answers, Washington DC, US Food and Drug Administration. US NAS  (1983)   Risk assessment in the federal government: managing the process, Washington DC, National Academy of Sciences, National Research Council.

２３３．VAN'T HOF, J. & SCHAIRER, L.A.  (1982)   Tradescantia assay systems for gaseous mutagens: a report of the US EnvironmentalProtection Agency Gene-Tox Program.  Mutat. Res., 99: 303-315.

２３４．VENITT, S. & CROFTON-SLEIGH, C.  (1981)  Mutagenicity of 42 coded compounds in a bacterial assay using  Escherichia coli and  Salmonella typhimurium.  In: de Serres, F.J. & Ashby, J., ed.  Evaluation of short-term tests for carcinogens, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 351-360 (Progress in Mutation Research, Vol. 1)

２３５．VENITT, S., FORSTER, R., & LONGSTAFF, E.  (1983)  Bacterial mutation assays. In: Dean, B.J., ed. Report of the UKEMS Sub-Committee on Guidelines for Mutagenicity Testing. Part 1. Basic Test Battery; Minimal Criteria; Professional Standards; Interpretation; Selection of Supplementary Assays, Swansea, United Kingdom Environmental Mutagen Society, pp. 5-40.

２３６．VIG, B.K.  (1982)  Soybean (Glycine max (L) merrill) as a short-term assay for study of environmental mutagens: a report of the US Environmental Protection Agency Gene-Tox Program. Mutat. Res., 99: 339-347.

２３７．VOGEL, E. & NATARAJAN, A.T.  (1979)  The relation between reaction kinetics and mutagenic action of mono-functional alkylating agents in higher eukaryotic systems. I. Recessive lethal mutations and translocations in  Drosophila. Mutat. Res., 62: 51-100.

２３８．VOGEL, E., BLIJLEVEN, W.G.H., KLAPWIJK, P.M., & ZIJLSTRA, J.A.  (1980)  Some current perspectives of the application of  Drosophila in the evaluation of carcinogens: In: Williams, G.M., Kroes, R., Waaijen, H.W., & van de Poll, K.W., ed.  The  predictive value of short-term screening tests, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 125-147.

２３９．VOGEL, E.W., ZIJLSTRA, J.A., & BLIJLEVEN, W.G.H.  (1983)  Mutagenic activity of selected aromatic amines and polycyclic hydrocarbons in  Drosophila melanogaster. Mutat. Res., 107: 53-77.

２４０．VOLLMAR, J.  (1977)  Statistical problems in mutagenicity tests.  Arch. Toxicol., 38: 13-25.

２４１．VON DER HUDE, W., BEHM, C., GUERTER., R., BASLER, A. (1988)  Evaluation of the SOS chromotest, Mutat. Res., 203, 81-94.

２４２．WALTER, E.  (1951)  [A few nonparametric test procedures.] Mathem. Statist., 3: 31-44 (in German).

２４３．WATERS, R., ASHBY, J., BARRETT, R.H., BURLINSON, B., MARTIN, C., & PENMAN, M.  (1984)  Unscheduled DNA synthesis. In: Dean, B.J., ed.  UKEMS Sub-Committee for Guidelines on Mutagenicity  Testing. Part II. Supplementary Tests, Swansea, United Kingdom Environmental Mutagen Society.

２４４．WATSON, J.D. & CRICK, F.H.C.  (1953)  Genetical implications of the structure of DNA.  Nature (Lond.), 171: 964-967.

２４５．WILCOX, P. & PARRY, J.M.  (1981)  The genetic activity of dinitropyrenes in yeast: unusual dose-response curves for induced mitotic gene conversion.  Carcinogenesis, 2: 1201-1208.

２４６．WILCOX, P., DANFORD, N., & PARRY, J.M.  (1982)  The genetic activity of dinitropyrenes in eukaryotic cells. In:  Mutagens in our environment, New York, Alan R. Liss, pp. 249-258.

２４７．WILKIE, D. & GOONESKERA, S.  (1980)  The yeast mitochondrial system in carcinogen testing.  Chem. Ind., 21: 847-850.

２４８．WILLIAMS, G.M.  (1977)  Detection of chemical carcinogens by unscheduled DNA synthesis in rat liver primary cell culture. Cancer Res., 37: 1845-1851.

２４９．WILLIAMS, G.M.  (1980)  Batteries of short-term tests for carcinogen screening. In: Williams, G.M., Kroes, R., Waaijers, H.W., & van de Poll, K.W., ed.  The predictive value of  short-term screening tests for carcinogenicity evaluation, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp 327-346.

２５０．WOLFF, S., ed.  (1982)   Sister chromatid exchange, New York, John Wiley and Sons.

２５１．WURGLER, F.E., GRAF, U., & BERCHTHOLD, W.  (1975)  Statistical problems connected with the sex-linked recessive lethal test in  Drosophila melanogaster.  I. The use of the Kastenbaum- Bowman test.  Arch. Genet., 48: 158-178.

２５２．WURGLER, F.E., SOBELS, F.H., & VOGEL, E.  (1977)   Drosophila: as assay system for detecting genetic changes. In: Kilbey et al., ed.  Handbook of mutagenicity test procedures, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp 335-373.

２５３．YAHAGI, T., NAGAO, M., SEINO, Y., MATSUSHIMA, T., SUGIMURA, T., & OKADA, M.  (1977)  Mutagenicities of  N-nitrosamines on  Salmonella. Mutat. Res., 48: 121-130.

２５４．YAMAMOTO, K. & KIKUCHI, Y.  (1980)  A comparison of diamaters of micronuclei induced by clastogens and by spindle poisons. Mutat. Res., 71: 127-131.

２５５．ZIJLSTRA, J.A. & VOGEL, E.W.  (1984)  Mutagenicity of 7,12-dimethylbenz( a)anthracene and some aromatic mutagens in Drosophila melanogaster. Mutat. Res., 125: 243-261.

２５６．ZIJLSTRA, J.A., VOGEL, E.W., & BREIMER, D.D.  (1984)  Strain-differences and inducibility of microsomal oxidative enzymes in  Drosophila melanogaster flies.  Chem.-biol. Interact., 48: 317-338.

２５７．ZIMMERMANN, F.K.  (1975)  Procedures used in the induction of mitotic recombination and mutation in the yeast  Saccharomyces  cerevisiae. Mutat. Res., 31: 71-86.

２５８．ZIMMERMANN, F.K. & SCHEEL, I.  (1981)  Induction of mitotic gene conversion in strain D7 of  Saccharomyces cerevisiae by 42 coded chemicals. In: de Serres, F.J. & Ashby, J., ed. Evaluation of short-term tests for carcinogens, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 481-490 (Progress in Mutation Research, Vol. 1).

２５９．ZIMMERMANN, F.K., KERN, R., & ROSENBERGER, H.  (1975)  A yeast strain for the simultaneous detection of induced crossing- over, mitotic gene conversion, and reverse mutation.  Mutat. Res., 28: 381-388.

２６０．ZIMMERMANN, F.K., MAYER, V.W., & PARRY, J.M.  (1982)  Genetic toxicology studies using  Saccharomyces cerevisiae. J. appl. Toxicol., 2: 1-10.

２６１．ZIMMERMANN, F.K., VON BORSTEL, R.C., PARRY, J.M., STIEBERT, D., ZETTERBERG, G., VON HALLE, E.S., BARALE, R., & LOPRIENO, N. (1984)  Testing of chemicals for genetic activity with  Saccharomyces cerevisiae:  report of the US Environmental Protection Agency Gene-Tox Program.  Mutat. Res., 133: 199-244.