AM	Sal./E.coli	Min ( 78.1μg//plate, +S9); Spe=1060 (TA98)	○	1)
CA	CHL/IU	Min ( 0.078 mg/ml,±S9); D20=0.073	◎	1)

1) Ministry of Labour, Japan, Mutagen. Test Data, of Exist. Chem. Subst., JETOC (Ed.) (1997) (Tabeles in English)

AM	Sal./E.coli	Max ( 5.0 mg/plate, ±S9)	□	1,2)
CA	CHL/IU	Max ( 1.9 mg/ml,±S9)　(only at low pH)	□	1)

1) Ministry of Health & Welfare (Ed):Toxicity Testing Reports of Environ. Chemicals, Vol.1 (1994) (Tabeles in English)
2) Ministry of Labour, Japan, Mutagen. Test Data, of Exist. Chem. Subst., JETOC (Ed.) (1996) (Tabeles in English)

AM	Sal.	Min(?)	◎	1)
CA	CHL/IU	Min( 2.0mg/ml, +S9), 3-21h: D20=4.0, TR=1.5	○	2)

1) Nagao M & Sugimura: T: Ann. Rev. Genet., 12, 117-159 (1978)
2) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test in vitro,  LIC, Tokyo (1998） (Tabeles in English)

● 2-Amino-3-methyl-9H-pyrideo (2,3-b) indole acetate (Me-AαC)
　 117831-29-5 Laboratry Carcinogen/Pyrolysate 　227.33

AM	Sal.	Min (?)	◎	1)
CA	CHL/IU	Min ( 0.125mg/ml, +S9), 3-21h; D20=0.18; TR=84	◎	2)

1) Nagao M & Sugimura: T: Ann. Rev. Genet., 12, 117-159 (1978)
2) Sofuni T. (Ed.): Data Book of Chromosomal　Aberration Test in vitro,  LIC, Tokyo (1998） (Tabeles in English)

● 2-Amino-1-naphthalenesulfonic acid　(Tobias acid, トビアス酸）
　 81-16-3 　Industry 　　223.25　　

AM	Sal./E.coli	Min ( 0.123 mg/plate, +S9)	○w	1)
CA	CHL/IU	Min ( 1.1 mg/ml, -S9), 6h	○w	1,)
CA	CHL/IU	Max ( 3.0 mg/ml, ±S9	□	2,)

1) Ministry of Health & Welfare (Ed):Toxicity Testing Reports of Environ. Chemicals, Vol. 3 (1996) (Tables in English)
2) Ministry of Labour, Japan, Mutagen. Test Data, of Exist. Chem. Subst., JETOC (Ed.) (1996)(Tabeles in English)

● 2-Amino-1,5-naphthalenesulfonic acid, disodium salt　(C acid）
　  14170-43-5　Industry 　　347.28　　

AM	Sal./E.coli	Max ( 5.0 mg/plate, ±S9)	□	1)
CA	CHL/IU	Max ( 3.0 mg/ml, ±S9	□	1, 2)

1) Ministry of Health & Welfare (Ed):Toxicity Testing Reports of Environ. Chemicals, Vol. 3 (1996)
2) Ministry of Labour, Japan, Mutagen. Test Data, of Exist. Chem. Subst., JETOC (Ed.) (1996)

● 8-Amino-1-naphthalenesulfonic acid
　  82-75-7　Industry 　　223.25　　

AM

Sal./E.coli

Max ( 2.0 mg/plate, ±S9); Spa=32.2

○w

1)

1) Ministry of Labour, Japan, Mutagen. Test Data, of Exist. Chem. Subst., JETOC (Ed.) (1996) (Tabeles in English)

● 2-Amino-4-nitrophenol　（2-アミノ-4-ニトロフェノール）
　  99-57-0　Laboratory　　154.13　　　

AM	Sal.	Min (?)	○	1)
CA	CHL/IU	Min ( 0.015mg/ml, -S9), 48h, D20=0.018; TR=800	◎	2)

1) Ishidate MJr, et al: Natl. Inst. Hygien. Scie. Tokyo, (?)　
2) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test in vitro LIC, Tokyo (1998) (Tabeles in English)

● 2-Amino-5-nitrophenol　（2-アミノ-5-ニトロフェノール）
　　　121-88-0　Cosmetics　154.13

AM	Sal./E.coli	Min (?)	○	1)
CA	CHL/IU	Min ( 0.00375mg/ml, -S9), 48h, D20=0.0052; TR=3200	◎	2)

1) Ishidate MJr, et al: Natl. Inst. Hygien. Scie. Tokyo, ?
2) Sofuni T. (Ed.): Data Book of Chromosomal　Aberration Test in vitro LIC, Tokyo (1998）(Tabeles in English)

● 3-Aminophenol（3-アミノフェノール）(m-Aminophenol, 3-Amino-1-hydroxybenzene)
　 591-27-5　Industry　109.13

AM	Sal./E.coli	Max ( 5.0 mg/plate, ±S9)	□	1)
CA	CHL/IU	Min ( 0.069mg/ml, -S9), 24h	○	1)

1) Ministry of Health & Welfare (Ed):Toxicity Testing Reports of Environ. Chemicals, Vol. 8(2) (2001) (Tabeles in English)

● 4-Aminophenol （4-アミノフェノール） （C.I. 76550, p-Hydroxyaniline)
　 123-30-8　Industry　　109.14

AM	Sal./E.coli	Max ( 5.0 mg/plate, ±S9)	□	1)
AM	Sal./E.coli	Min ( 1.25. mg/plate, +S9; Spe=60.8 (E..coli)	○	2)
CA	CHL/IU	Min ( 0.005 mg/ml, -S9), 24h	○	1,2)
CA	CHL/IU	Min ( 0.005 mg/ml, -S9), 24h; D20=0.00078; TR=21000	◎	3)
MLA	L5178Y	Min ( 3 μg/ml, -S9)	○	4)

1) Ministry of Health & Welfare (Ed):Toxicity Testing Reports of Environ. Chemicals, Vol. 5 (1997) (Tabeles in English)
2) Ministry of Labour, Japan, Mutagen. Test Data, of Exist. Chem. Subst., JETOC (Ed.) Suppl. 2 (2000) (Tabeles in English)
3) Ministry of Labour, Japan; Japan Bioassay Res. Center, Ann. Rep. (2005); Ministry of Labour, Japan, Mutagen. Test Data, of Exist. Chem. Subst., JETOC (Ed.) Suppl.4, p.180 (2008) (Tabeles in English)
4) Oberly TJ., et al., Mutation Res., 125, 291-306 (1984)

● Aminophylline (Theophyllamine)   
    317-34-0　　Medicine　　420.43    

SM

(?)

Min (?)

○

1)

1) Huberman E & Sacks L: Proc. Natl. Acad. Sci., 73, 188-92 (1976)

● 1-Amino-2-propanol （1-アミノ-2-プロパノール）
  　78-96-6　　Medicine　　75.11

AM

Sal./E.coli

Max ( 5.0 mg/plate, ±S9)

□

1)

2) Ministry of Labour, Japan, Mutagen. Test Data, of Exist. Chem. Subst., JETOC (Ed.) Suppl. 3 (2005) (Tabeles in English)
 
● 2-Aminopurine  （アミノプリン）         
    452-06-2　Laboratory　135.13

AM	Sal./E. coli	Min (?)	○	1)
MB	Fungi	Min ( 5 μｇ/ml)	○	2)
MB	Fungi	Min (?)	○	3)
PLNv	Barley	Min (?)	○w	4)
MLA	L5178Y	Min ( 125 μｇ/ml)	○	5)

1) Janion C., Mutation Res., 56, 225-234 (1978)
2) Brockman HE & De Serres FJ., Genetics, 48, 597-604 (1963
)3) De Serres FJ., et al., Basic Life Sci., 31, 381-389 (1985)
4) Nilan RA: The Cytolory and Genetics of Barley, Washington State Univ., pp.65 (1964)
5) Clive D., et al., Mutation Res., 59, 61-108 (1979)

● Aminopyridine (アミノピリジン）
    504-29-0　　Industry　　94.11

　 US-NTP Genotoxicity Screening；
  　○　Ames Test: □

● 2-Amino-9H-pyrido (2,3-b) indole acetate　（Glob-P-1 Acetate; AαC)
　 122001-30-3  Carcinogen/Pyrolysate 　243.26

AM	Sal.	Min (?)	○	1)
CA	CHL/IU	Min ( 0.5 mg/ml, +S9), 3-21h, D20=0.71; TR=14 Min ( 0.06 mg/ml, -S9), 48h; Poly: PD20=0.021	○	2)

　1) Nagao M & Sugimura: T: Ann. Rev. Genet., 12, 117-159 (1978)
　2) Sofuni T. (Ed.): Data Book of Chromosomal　Aberration Test in vitro LIC, Tokyo (1998） (Tabeles in English)

● 4-Aminopyrine （４−アミノピリン）
　  58-15-1 　　Medicine 　　231.30

AM	Sal.	Max ( 4.62 mg/plate, -S9)	□	1)
CA	Don	Max ( 10-3 M)	□	2)
SCE	Don	Max ( 10-4 M)	□	3)

1) Aisawa M. et al: Mutation Res. 57, 287 (1978)
2) Abe S & Sasaki M: J. Natl. Cancer Inst., 58, 1635-1641 (1977)

● 4-Aminoquinoline-1-oxide (4-AQO)　（4-アミノキノリン-1-オキサイド）
　   2508-86-3　　Laboratory　　160.18

AM	Sal.	Min (?)	○	1)
CA	CHL/IU	Min ( 0.20 mg/ml, -S9), 24h, D20=0.28; TR=210	◎	2)

1) Ishidate MJr, et al: Natl. Inst. Hygien. Scie. Tokyo, (?)
2) Sofuni T. (Ed.): Data Book of Chromosome　Aberration Test in vitro LIC, Tokyo (1998） (Tabeles in English)

●Top Page　（トップページ） ●Abbreviation 　（省略記号）　 ●Mutagenicity （変異原性） ●Test Systems　(試験法の種類） ●Technical Problems　（技術的問題点） ●List of　Compounds（化合物リスト） ●Evaluation of Results　（試験結果の評価）