@@@@@@@@@@@@@@
Group C-2 ‰»Šw\‘’@(Chemical Structure)  
œ Calcium citrate iΈ΄έŽ_ƒJƒ‹ƒVƒEƒ€j@@@@@ @@
@@
@CAS: 813-94-5 @ Food@ MW: 570.51
AM Sal. Max ( 10.0 mg/plate, }S9)@
 
1, 2)
CA CHL/IU Max ( 6.0 mg/ml, -S9), 24-48h
 
3)
1) Ishidate MJr. (Ed.): Data Book of Mutagenicity Tests on Chemicals in Bacteria, LIC/Japan (1991)
2) ‚h‚“‚ˆ‚‰‚„‚‚”‚…@‚l‚i‚’, et al., Mutagenicity Tests on Food Additives, Toxicol. Forum, Vol. 7(6) (1984) (in Japanese)
3)
Sofuni T. (Ed.): Data Book of Chromosomal@Aberration Test In Vitro,, LIC, Tokyo (1998)

œ Calcium cynamide iƒJƒ‹ƒVƒEƒ€ƒVƒAƒiƒ~ƒhj@@@@@@ @@
@@156-62-7 Industry@ 80.11

US-NTP Genotoxicity ScreeningF

›@Ames TestF@
›w or ’
›@
MLA TestF@ 
›@SLRL Test with Drosophila:@
 
›@
CA Test with CHO CellsF@ 
›@
SCE Test with CHO CellsF 
œ Calcium gluconate iƒOƒ‹ƒRƒ“Ž_ƒJƒ‹ƒVƒEƒ€j@@@@@ @@
@@@
299-28-5@ Food@ 448.39
AM Sal. Max ( 5.0 mg/plate, }S9)
 
1-3)
CA CHL/IU Max ( 4.0 mg/ml, -S9), 24-48h
 
4)
1) Ishidate MJr. (Ed.): Data Book of Mutagenicity Tests on Chemicals in Bacteria, LIC/Japan (1991)
2) Fujita H & Sasaki M.: Ann. Rep. Tokyo Metr. Res. Lab. P.H., 38, 423-430 (1987)@(in Japanese)
3) ‚h‚“‚ˆ‚‰‚„‚‚”‚…@‚l‚i‚’, et al., Mutagenicity Tests on Food Additives, Toxicol. Forum, Vol. 7(6) (1984) (in Japanese)
4)
Sofuni T. (Ed.): Data Book of Chromosomal@Aberration Test In Vitro, LIC, Tokyo (1998)

œ Calcium glycerophosphate (Neurosin)@iƒOƒŠƒZƒ—ΣŽ_ƒJƒ‹ƒVƒEƒ€j@@@@ @@ @@@
@@@@@
@@ 27214-00-2@ Food/Medicine@ 210.15

AM Sal. Max ( 5.0 mg/plate, }S9)@@@
 
1, 2)
CA CHL/IU Max ( 2.0 mg/ml, -S9), 24-48h
 
3)
1) ‚h‚“‚ˆ‚‰‚„‚‚”‚…@‚l‚i‚’, et al., Mutagenicity Tests on Food Additives, Mutagen & Toxicol., 4, 80-89 (1981)(in Japanese)
2) Fujita H & Sasaki M.: Ann. Rep. Tokyo Metr. Res. Lab. P.H., 38, 423-430 (1987)@(in Japanese)
3)
Sofuni T. (Ed.): Data Book of Chromosomal@Aberration Test In Vitro, LIC, Tokyo (1998)

œ Calcium hydroxide @i…Ž_‰»ƒJƒ‹ƒVƒEƒ€j@@ @@
@@
1305-62-0 Food @ 74.09
AM Sal. Max (10.0 mg/plate, }S9)@
 
1, 2)
CA CHL/IU Max ( 0.25 mg/ml, -S9), 24-48h
 
3)
1) Ishidate MJr. (Ed.): Data Book of Mutagenicity Tests on Chemicals in Bacteria, LIC/Japan(1991)
2) Fujita H & Sasaki M.: Ann. Rep. Tokyo Metr. Res. Lab. P.H., 40, 355-362 (1989)@(in Japanese)
3)
Sofuni T. (Ed.): Data Book of Chromosomal@Aberration Test In Vitro, LIC, Tokyo (1998)

œ Calcium hypochlorite @(ŽŸˆŸ‰–‘fŽ_ƒJƒ‹ƒVƒEƒ€j@ @@
@@
7778-54-3 @Food @ 142.98
AM Sal. Max (1.0 mg/plate, }S9)
 
1)
CA CHL/IU Min ( 0.06mg/ml, -S9), 24-48h, D20=0.064, TR=170
›
2)
MNv Mice Max ( 40 mg/kg x4, ip ) 24h
 
3)
1) Ishidate MJr. (Ed.): Data Book of Mutagenicity Tests on Chemicals in Bacteria, LIC/Japan (1991)
2)
Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test i In Vitro,, LIC, Tokyo (1998j
3) Hayashi M., et al.; Fd. Chem. Toxic., 26, (6), 487-500 (1988)

œ Calcium pantothenate iƒpƒ“ƒgƒeƒ“Ž_ƒJƒ‹ƒVƒEƒ€j
@
@137-08-6@Food @ 142.98
AM Sal Max (10.0 mg/plate, }S9)
 
1, 2)
CA CHL/IU Max ( 6.0 mg/ml, -S9), 24-48h
 
3)
1) Ishidate MJr. (Ed.): Data Book of Mutagenicity Tests on Chemicals in Bacteria, LIC/Japan (1991)
2)
Fujita H & Sasaki M.: Ann. Rep. Tokyo Metr. Res. Lab. P.H., 38, 423-430 (1987)@(in Japanese)
3)
Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro,, LIC, Tokyo (1998j

œ Calcium phophate, dibasici—ΣŽ_ƒJƒ‹ƒVƒEƒ€A“ρ‰–Šξj
@@
7757-93-9@ Food @ 136.06
AM Sal Max ( 10.0 mg/plate, }S9)@
 
1, 2)
CA CHL/IU Max ( 0.5 mg/ml, -S9), 24-48h,
 
3)
1) ‚h‚“‚ˆ‚‰‚„‚‚”‚…@‚l‚i‚’, (Ed.): Data Book of Mutagenicity Tests on Chemicals in Bacteria, LIC/Japan (1991)
2) Fujita H & Sasaki M.: Ann. Rep. Tokyo Metr. Res. Lab. P.H., 40, 355-362 (1989)@(in Japanese)
3) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test in vitro, LIC, Tokyo (1998j


œ Calcium phophate, monobasic@i—ΣŽ_ƒJƒ‹ƒVƒEƒ€Aˆκ‰–Šξj

@@7758-23-8@ Food @ 234.05
AM Sal Max ( 10.0 mg/plate, }S9)@
 
1, 2)
CA CHL/IU Max ( 2.5 mg/ml, -S9), 24-48h, (No data for +S9)
 
3)
1)@‚h‚“‚ˆ‚‰‚„‚‚”‚…@‚l‚i‚’, (Ed.): Data Book of Mutagenicity Tests on Chemicals in Bacteria, LIC/Japan (1991)
2) Fujita H & Sasaki M.: Ann. Rep. Tokyo Metr. Res. Lab. P.H., 38, 423-430 (1987)@(in Japanese)

3)
Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro, LIC, Tokyo (1998j

œ Calcium propionate iƒvƒƒsƒIƒ“Ž_ƒJƒ‹ƒVƒEƒ€j
@@
4075-81-4@ Food @ 186.22
AM Sal Max ( 10.0 mg/plate, }S9)@
 
1, 2)
CA CHL/IU Max ( 2.0 mg/ml, -S9), 24-48h,
’
3)
1) ‚h‚“‚ˆ‚‰‚„‚‚”‚…@‚l‚i‚’, (Ed.): Data Book of Mutagenicity Tests on Chemicals in Bacteria, LIC/Japan (1991)
2) Fujita H & Sasaki M.: Ann. Rep. Tokyo Metr. Res. Lab. P.H., 42, 267-275 (1991)@(in Japanese)

3)
Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro,, LIC, Tokyo (1998j

œTop Page@iƒgƒbƒvƒy[ƒWj
œAbbreviation @iΘ—ͺ‹L†j@
œMutagenicity i•ΟˆΩŒ΄«j
œTest Systems@(ŽŽŒ±–@‚ΜŽν—ށj
œTechnical Problems@i‹Zp“I–β‘θ“_j
œList of@Compoundsi‰»‡•¨ƒŠƒXƒgj
œEvaluation of Results@iŽŽŒ±Œ‹‰Κ‚Μ•]‰Ώj