Group I-2 化学構造 (Chemical Structure)  
● Isoamyl isovalerate イソ吉草酸イソアミル
 
  CAS: 659-70-1  Food  MW: 172.27
AM Sal Max ( 10.0 mg/plate, ±S9)
1- 3)
CA CHL/IU Max ( 0.25 mg/ml, -S9), 24, 48h (No data for +S9)
4)
1) Ishidate MJr (Ed): Data Book of Mutagenicity Tests on Chemicals in Bacteria, LIC/Tokyo (1991) (Tables in English)
2) Ishidate MJr. et al., Mutagens & Toxicity: 5, 579-587 (1982) (in Japanese)
 
3) Fujita H & Sasaki M: Ann. Rep. Tokyo Metr. Res. Labl P.H., 38, 423-430 (1987)
4)
Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro LIC/Tokyo (1998) (Tables in English)

● Isoamyl propionate プロピオン酸イソアミル

 
  105-68-0 Food  144.21
AM Sal Max ( 10.0 mg/plate, ±S9)
1)
CA CHL/IU Max ( 0.25 mg/ml, -S9), 24, 48h (No data for +S9)
2)
1) Ishidate MJr (Ed): Data Book of Mutagenicity Tests on Chemicals in Bacteria, LIC/Tokyo (1991) (Tables in English)
2)
Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro LIC/Tokyo (1998) (Tables in English)

● Isobutene イソブテン
115-11-7  Industry  56.10
AM Sal/E. coli Max ( 48% ±S9) (in vapor)
1)
1) Ministry of Labor, Japan, Mutagenicity Test Data of Exist. Chem. Subst., JETOC (Ed.) Suppl.2 (2000) (Tables in English)

● Isobutyl alcohol イソブチル アルコール
 
  
78-83-1  Industry/Solvent   74.12
AM E.coli (CA274) Min ( 0.7% -S9) (in vapor)
1)
AM Sal/E.coli Max ( 5.0 mg/plate, ±S9) 2)
1) WHO, IPCS:, pp. 93-118, Environ. Health Criteria 65, WHO, Geneva (1987)
2) Japan Bioassay Research Center, Ann. Rep. (2005)

 
 US-NTP Genotoxicity Screening:
  ○Ames Test:


N-Isobutyl-N-(benzoylaminomethyl) nitrosamine
   
64005-59-0  Laboratory  235.29
CA CHL/IU Max ( 0.25 mg/ml, -S9), 24, 48h; (No data for +S9)
1)
1) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro LIC/Tokyo (1998) (Tables in English)

● Isobutyl p-hydroxybenzoate
パラオキシ安息香酸イソブチル
    
4247-02-3 Food   194.25
AM Sal Max ( ?)
1)
CA CHL/IU Max ( 0.06 mg/ml, -S9), 24, 48h (No data for +S9)
2)
1) Natl. Inst. Hygien. Sci., Tokyo, (?)
2) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro,  LIC, Tokyo (1998) (Tables in English)

N-Isobutyl-N'-nitroguanidine
 (-イソブチル-N'-ニトログアニジン
    
35089-66-8 Laboratory   160.18
CA CHL/IU Max ( 0.5 mg/ml, -S9), 24, 48h (No data for +S9)
1)
1) Ishidate MJr (Ed.): Data Book of Chromosomal Aberration Test In Vitro LIC/Tokyo; Elsevier/Amsterdam (1988)

N-Isobutyl-N'-nitro-N-nitrosoguanidine
N-イソブチル-N-ニトロ-N-ニトロソグアニジン
    
5461-85-8 Laboratory  189.21
AM Sal Max (?)
1)
CA CHL/IU Min ( 0.06 mg/ml, -S9), 24h(No data for +S9);
D
20= 0.014; TR= 770
2)
1) Natl. Inst. Hygien. Sci., Tokyo, (?)
2) Ishidate MJr (Ed.): Data Book of Chromosomal Aberration Test In Vitro LIC/Tokyo; Elsevier/Amsterdam (1988)

N-Isobutyl-N-nitrosourea N-イソブチル-N-ニトロソ尿素
    
760-60-1 Laboratory   145.16
AM Sal Min (?)
1)
CA CHL/IU Min ( 0.125 mg/ml, -S9), 24, 48h (No data for +S9);
D
20= 0.11; TR= 200
2)
1) Natl. Inst. Hygien. Sci., Tokyo ?
2) Ishidate MJr (Ed.): Data Book of Chromosomal Aberration Test In Vitro LIC/Tokyo; Elsevier/Amsterdam (1988)

N-Isobutyl-N-nitrosourethane N-イソブチル-N-ニトロソ ウレタン

  
33124-25-3 Laboratory 174.21
AM Sal Min (?)
1)
CA CHL/IU Min ( 0.063 mg/ml, -S9), 24, 48h(No data for +S9);
D
20= 0.1; TR= 140
2)
1) Natl. Inst. Hygien. Sci., Tokyo, (?)
2) Ishidate MJr (Ed.): Data Book of Chromosomal Aberration Test In Vitro LIC/Tokyo; Elsevier/ Amsterdam (1988)

● Isobutyl urea イソブチル 尿素

   
592-17-6 Lavoratory   116.16
AM Sal Max (?)
1)
CA CHL/IU Max ( 2.0 mg/ml, -S9), 24, 48h (No data for +S9)
2)
1) Natl. Inst. Hygien. Sci., Tokyo, (?)
2) Ishidate MJr (Ed.): Data Book of Chromosomal Aberration Test In Vitro LIC/Tokyo; Elsevier/ Amsterdam (1988)

N-isobutyl urethane イソブチル ウレタン

   
539-89-9  145.21
CA CHL/IU Max ( 4.0 mg/ml, -S9), 24, 48h (No data for +S9)
1)
1) Ishidate MJr (Ed.): Data Book of Chromosomal Aberration Test In Vitro LIC/Tokyo; Elsevier/ Amsterdam (1988)

N-isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol
   
25265-77-4  216.32
AM Sal/E.coli Max ( 0.625 mg/plate, ±S9)
1)
1) Ministry of Labour, Japan, Mutagenicity Test Data of Exist. Chem. Subst., JETOC (Ed.) Suppl. .2 (2000) (Tables in English)

Isobutyronitrile  (イソブチロニトリル
    78-82-0 Industry   69.11
AM SalE.coli Min (1.25 mg/plate, ±S9); spa= 278 (TA100)
1)
CA CHL/IU Max ( 0.70 mg/ml, ±S9), 6-18h
2)
1) Ministry of Labour, Japan, Mutagenicity Test Data of Exist. Chem. Subst., JETOC (Ed.) Suppl. .2, pp. 193 (2005) (Tables in English)
2) Ministry of Labour, Japan, Mutagenicity Test Data of Exist. Chem. Subst., JETOC (Ed.) Suppl. .2, pp. 262 (2005) (Tables in English)

Isocyanuric acid (イソシアヌル酸) (Cyanuric acid/s-Triazine-2,4,6-triol)
    108-80-5 Industry   129.09
CA CHL/IU Max ( 1.3 mg/plate, ±S9), 24, 48h, -S9; 6-18h, ±S9)
1)
1) Ministry of Health & Welfare, Japan:  Tox. Test. Rep. of Environ. Chem., Vol. 5., pp .407 (1997) (Tables in English)
 
Top Page (トップページ)
Abbreviation  (省略記号) 
Mutagenicity  (変異原性)
Test Systems (試験法の種類)
Technical Problems (技術的問題点)
List of Compounds(化合物リスト)
Evaluation of Results (試験結果の評価)